Glucocorticoid tapering pace in microscopic polyangiitis and granulomatosis with polyangiitis in Japanese real-world practice: A propensity score-matched retrospective cohort study from the J-CANVAS registry
The glucocorticoid tapering for MPA and GPA in Japanese real-world practice was found to be generally slower than the standard regimen revealing a huge evidence-practice gap. Additionally, slower tapering did not improve relapse-free survival and might cause unnecessary glucocorticoid exposure.
Authors
- Naoho Takizawa (ORCID: https://orcid.org/0000-0003-3744-3537)
- Ryo Nishioka (ORCID: https://orcid.org/0000-0001-8654-7311)
- Yutaka Kawahito (ORCID: https://orcid.org/0000-0002-3860-0488)
- Toshiko Ito‐Ihara (ORCID: https://orcid.org/0000-0001-7152-3026)
- Tomoaki Takata (ORCID: https://orcid.org/0000-0003-2959-6015)
- Yasuhiro Shimojima (ORCID: https://orcid.org/0000-0001-7100-1121)
- Takashi Kawaguchi (ORCID: https://orcid.org/0000-0003-2446-7716)
- Kunihiro Ichinose (ORCID: https://orcid.org/0000-0001-8794-7106)
- Tohru Takeuchi (ORCID: https://orcid.org/0000-0002-0065-929X)
- Takashi Kida (ORCID: https://orcid.org/0000-0002-5740-8352)
- Yasuhiko Yamano (ORCID: https://orcid.org/0000-0002-7779-9215)
- Satoshi Ōmura (ORCID: https://orcid.org/0000-0002-9187-2044)
- Kiyoshi Matsui (ORCID: https://orcid.org/0000-0002-1146-4172)
- Yuji Kukida (ORCID: https://orcid.org/0000-0003-4074-4533)
- Daiki Nakagomi (ORCID: https://orcid.org/0000-0003-1682-9799)
- Naoya Kondo (ORCID: https://orcid.org/0000-0002-8082-8849)
- Yoshia Miyawaki (ORCID: https://orcid.org/0000-0002-6981-3443)
- Ichiro Mizushima (ORCID: https://orcid.org/0000-0002-6231-0683)
- Nobuyuki Yajima (ORCID: https://orcid.org/0000-0002-8292-3962)
- Ryo Yanai (ORCID: https://orcid.org/0000-0003-3118-7675)
- Shintaro Hirata (ORCID: https://orcid.org/0000-0002-2474-9943)
- Takuya Yanagida (ORCID: https://orcid.org/0000-0001-9052-4841)
- Masaru Kato (ORCID: https://orcid.org/0000-0002-2023-6585)
- Yoshiyuki Abe (ORCID: https://orcid.org/0000-0002-1014-2868)
- Atsushi Nomura (ORCID: https://orcid.org/0000-0002-8194-6273)
- Takafumi Ito (ORCID: https://orcid.org/0000-0003-0677-6566)
- Ryota Okazaki
- Koji Endo
- Mayuko Moriyama
- Ayuko Takatani
- Masatoshi Kadoya
- Yusuke Matsuo
Institutions
- Kanazawa University (JP)
- SHOWA Medical University (JP)
- Tokyo Medical and Dental University (JP)
- Fukushima Medical University (JP)
- Hyogo Medical University (JP)
- Shinshu University (JP)
- Tokyo University of Pharmacy and Life Sciences (JP)
- Okayama University (JP)
- Shimane University (JP)
- Hokkaido University (JP)
- Kyoto University (JP)
- Tottori University of Environmental Studies (JP)
- Juntendo University (JP)
- Kyoto Prefectural University of Medicine (JP)
- St. Luke's International Hospital (JP)
- Chubu Rosai Hospital (JP)
- Sasebo City General Hospital (JP)
- Kanazawa University Hospital (JP)
- University of Yamanashi Hospital (JP)
- Kagoshima University Hospital (JP)
- Hiroshima University Hospital (JP)
- Kure Kyosai Hospital (JP)
- Tottori Prefectural Central Hospital (JP)
- Kyoto first Red Cross hospital (JP)
- University Hospital Kyoto Prefectural University of Medicine (JP)
- Shinshu University Hospital (JP)
- Kyoto Katsura Hospital (JP)
- Shimane University Hospital (JP)
- Japanese Red Cross Society Kyoto Daini Hospital (JP)
- Tosei General Hospital (JP)
- Nagasaki University (JP)
- Tottori University (JP)
- Osaka University of Pharmaceutical Sciences (JP)
Publication Details
- Journal
- Modern Rheumatology
- Published
- 2024-12-24
- DOI
- https://doi.org/10.1093/mr/roae112
- Primary Topic
- Vasculitis and related conditions
- Type
- article
- Field-Weighted Citation Impact
- 0.00