An effective strategy with tofacitinib for the management of focal myositis with rheumatoid arthritis: a case report

Focal myositis is a rare, localized, benign, self-limiting, and non-suppurative inflammatory lesion of the skeletal muscle that may occasionally occur as a complication of rheumatic diseases. This case report discusses a 58-year-old patient with rheumatoid arthritis, who was diagnosed with focal myositis during standard immunosuppressive therapy. The patient was treated with tofacitinib; to our knowledge, this is the first reported case of focal myositis managed with this medication. Clinicians should maintain a suspicion for focal myositis in patients presenting with localized muscle swelling and pain, especially those with underlying rheumatic conditions. In cases where corticosteroid tapering proves difficult, tofacitinib may be considered as an alternative therapeutic strategy.

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Publication Details

Journal
Frontiers in Immunology
Published
2024-12-24
DOI
https://doi.org/10.3389/fimmu.2024.1502410
Citations
1
Primary Topic
Inflammatory Myopathies and Dermatomyositis
Type
article
Field-Weighted Citation Impact
0.39
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article

An effective strategy with tofacitinib for the management of focal myositis with rheumatoid arthritis: a case report

Haihong Zheng, Jing Pan, Shaobiao Pan, Juan Xu
1 citations
Frontiers in Immunology
Inflammatory Myopathies and Dermatomyositis
0.39
article

An effective strategy with tofacitinib for the management of focal myositis with rheumatoid arthritis: a case report

Haihong Zheng, Jing Pan, Shaobiao Pan, Juan Xu
article en
1 citations

Abstract

Focal myositis is a rare, localized, benign, self-limiting, and non-suppurative inflammatory lesion of the skeletal muscle that may occasionally occur as a complication of rheumatic diseases. This case report discusses a 58-year-old patient with rheumatoid arthritis, who was diagnosed with focal myositis during standard immunosuppressive therapy. The patient was treated with tofacitinib; to our knowledge, this is the first reported case of focal myositis managed with this medication. Clinicians should maintain a suspicion for focal myositis in patients presenting with localized muscle swelling and pain, especially those with underlying rheumatic conditions. In cases where corticosteroid tapering proves difficult, tofacitinib may be considered as an alternative therapeutic strategy.

Frontiers in ImmunologyVol. 15
Wenzhou Medical University (CN)
Good health and well-being
Openalex Percentile: Top 31%
Inflammatory Myopathies and Dermatomyositis
0.39
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