Prognosis and prevention of recurrent and atypical endometrial hyperplasia in women of reproductive age

Based on the analytical review of the literature, the approaches to the issues of prognosis and prevention of recurrent and atypical endometrial hyperplasia were systematized by identifying the main markers of cellular regulatory activity. Preoncological lesions of the endometrium can be predicted using the main diagnostic �tools�: hormonal background studies, since hyperestrogen-ism is the main element of the mechanism of endometrial hyperplasia development; ultrasound diagnostics; magnetic resonance imaging, immunohistochemical studies, biomarker studies, com-puter morphometry, etc. However, a complete diagnosis is possible only with a morphological study that establishes the criteria for cellular and tissue pathological changes. Histological exami-nation of chronic endometritis in women of reproductive age reveals disorders of proliferation and secretion of the endometrium, provoking the development of endometrial hyperplasia. The necessary measures aimed at preventing recurrence of endometrial hyperplasia and reducing the risk of developing atypical endometrial hyperplasia in women of reproductive age are in time di-agnosis and treatment of inflammatory diseases of the pelvic organs, correction of hormonal dis-orders, control over body weight and its correction, annual examinations by a gynecologist, ultra-sound of the pelvic organs, observation by a general practitioner and endocrinologist in the pres-ence of risk factors for the development of endometrial hyperplasia.