Network pharmacology-based strategy to reveal Acacetin against lipopolysaccharide-induced lung injury
The combination of network pharmacology and experimental studies revealed the role of Acacetin in improving ALI via the AMPK/Nrf2/HMGB1 signaling axis, which provided new insights into the treatment of ALI with Acacetin as a candidate drug.
Authors
- Wencheng Zhou (ORCID: https://orcid.org/0000-0001-6160-4551)
- Liucheng Li (ORCID: https://orcid.org/0000-0002-2511-0156)
- Zhihui Zhang (ORCID: https://orcid.org/0000-0002-1648-0040)
- Jiangbei Li
- Yuzhen Wang (ORCID: https://orcid.org/0000-0002-6315-2437)
- Zhisen Wang (ORCID: https://orcid.org/0000-0003-4560-7773)
- Ting Yan
Institutions
- Zhejiang Chinese Medical University (CN)
- Xuzhou Medical College (CN)
- Shanghai Jiao Tong University (CN)
- Sir Run Run Shaw Hospital (CN)
- Shanghai University of Traditional Chinese Medicine (CN)
- Zhejiang Hospital (CN)
- Second People’s Hospital of Huai’an (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- International Immunopharmacology
- Published
- 2024-12-24
- DOI
- https://doi.org/10.1016/j.intimp.2024.113843
- Primary Topic
- Medicinal plant effects and applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00