PENGARUH VARIASI KONSENTRASI ASAM BASA TERHADAP SIFAT FISIK DAN STABILITAS GRANUL EFFERVESCENT EKSTRAK DAUN KATUK (Sauropus androgynus (L) Merr.)

The Aims of this study was to determine the effect of variations in acid-base concentration on the physical properties of effervescent granules of sauropus androgynus L. katuk leaf extract. Experimental research design was used as the research design. Effervescent granules were formulated in three formulations using variations in acid base concentration F1 (28,3:20,2), F2 (30,3:18,2), F3 (32,3:16,2). The effervescent granules were evaluated for their physical properties including organoleptic, flow rate, water content, dissolving time, pH, and stability test at room temperature (25±2oC) and hot temperature (40±2oC) in formulation 1. The organoleptic test was observed visually. Observations of flow rate, water content, dissolving time, pH, and stability test were observed with one way anova statistics. The results showed that the acid-base variation had no effect on organoleptic physical properties, water content and flow rate but affected the physical properties of dissolving time and pH. The stability test on formulation 1 was unstable during 28 days storage.