A Novel Approach to Potentially Improving Soft-Tissue Sarcoma Survival: Prophylactic Lung Radiotherapy Inhibits Growth of Lung Metastases and Prolongs Survival in a Murine Soft-Tissue Sarcoma Model
Prophylactic WLI after resection of the primary tumor to inhibit the growth of pulmonary metastases from previously entrapped CTCs may be a promising approach to improve survival for patients with localized high-risk STS.
Authors
- Kayla M. Tighe
- Andrea Casildo
- Vincent Y. Ng (ORCID: https://orcid.org/0000-0002-4861-5528)
- France Carrier (ORCID: https://orcid.org/0000-0002-5517-5284)
- Kai Jiang (ORCID: https://orcid.org/0000-0001-5013-4187)
- Kevin P. Byrne (ORCID: https://orcid.org/0000-0002-6368-154X)
- Michael Edward Kallen (ORCID: https://orcid.org/0000-0002-0470-7922)
- Brandon Carter‐Cooper
- Katharina Richard (ORCID: https://orcid.org/0000-0003-0939-2103)
- Rena G. Lapidus (ORCID: https://orcid.org/0000-0002-4422-743X)
- Antonino Passaniti (ORCID: https://orcid.org/0000-0002-9467-0309)
- Xin-Rong Ma
- K. Fisher
- J. R. Blanton
- Alexander Ruditsky
Institutions
- University of Maryland, Baltimore (US)
- University of Maryland Medical Center (US)
- Frederick National Laboratory for Cancer Research (US)
- University of Baltimore (US)
Publication Details
- Journal
- Cureus
- Published
- 2024-12-24
- DOI
- https://doi.org/10.7759/cureus.76334
- Primary Topic
- Sarcoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- New York City Department of Health and Mental Hygiene
- Maryland Department of Health and Mental Hygiene
- National Cancer Institute