Human pluripotent stem cell-derived microglia shape neuronal morphology and enhance network activity in vitro
Our findings underscore the importance of including hPSC-derived microglia in in vitro models to better simulate in vivo neuroglial interactions and provide a platform for investigating neuron-glia dynamics in health and disease.
Authors
- Vivi M. Heine (ORCID: https://orcid.org/0000-0003-4416-3875)
- Koen Helwegen (ORCID: https://orcid.org/0000-0002-1247-6626)
- Liza Martha Linda Kok
- Nicki Coveña
Institutions
- Amsterdam Neuroscience (NL)
- Cognitive Research (United States) (US)
- Vrije Universiteit Amsterdam (NL)
Publication Details
- Journal
- Journal of Neuroscience Methods
- Published
- 2024-12-25
- DOI
- https://doi.org/10.1016/j.jneumeth.2024.110354
- Citations
- 1
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.25