Loss of glomerular aldolase B in diabetic nephropathy promotes renal fibrosis via activating Akt/GSK/β-catenin axis
Our findings reveal a novel non-metabolic role of glomerular ALDOB in protecting against podocyte injury and renal fibrosis.
Authors
- Shuang Qu (ORCID: https://orcid.org/0009-0008-9889-3383)
- Song Jiang (ORCID: https://orcid.org/0000-0002-7656-9434)
- Xuan Ji (ORCID: https://orcid.org/0000-0001-8131-5394)
- Tingting Zhao (ORCID: https://orcid.org/0000-0003-3787-2016)
- S. Peng (ORCID: https://orcid.org/0009-0006-0888-3460)
- Zen Ke (ORCID: https://orcid.org/0000-0002-7382-6810)
- Zhihong Liu (ORCID: https://orcid.org/0000-0001-5237-7772)
- Minghui Liu (ORCID: https://orcid.org/0000-0002-1803-2452)
- Wenwen Yang (ORCID: https://orcid.org/0000-0002-0367-0128)
- Mingchao Zhang
Institutions
- China Pharmaceutical University (CN)
- Nanjing General Hospital of Nanjing Military Command (CN)
- Nanjing Drum Tower Hospital (CN)
- Jinling Institute of Technology (CN)
- Nanjing Medical University (CN)
- Nanjing University (CN)
Publication Details
- Journal
- Journal of Advanced Research
- Published
- 2024-12-24
- DOI
- https://doi.org/10.1016/j.jare.2024.12.027
- Citations
- 1
- Primary Topic
- Chronic Kidney Disease and Diabetes
- Type
- article
- Field-Weighted Citation Impact
- 0.34
Funders
- National Natural Science Foundation of China
- Key Technologies Research and Development Program
- National Key Research and Development Program of China