Quantifying sampling method-induced imprecision in user-friendly lateral upper arm blood collection: Introducing σ3-methodology (S3) for the verification of alternative sampling methods with TAP® II as a use case

Alternative blood sampling innovations hold promise for advancing diagnostic care, aiming to deliver accessible decentralised sample collection at home that does not require phlebotomist involvement. However, sampling method-induced imprecision should not be overlooked in the performance assessment to guarantee responsible development that will contribute to the success and desirable societal impact of alternative sampling technologies.