Heterogeneity of cancer-associated fibroblast subpopulations in prostate cancer: Implications for prognosis and immunotherapy
This investigation illuminates the critical potential of targeting CAFs to augment immunotherapeutic approaches in prostate cancer. Our findings contribute to a deeper understanding of the TME's complexity, advocating for further exploration into CAF-targeted therapies aimed at enhancing treatment responses and ultimately improving patient outcomes.
Authors
- Jian‐Ge Wang (ORCID: https://orcid.org/0000-0003-3493-6694)
- Zhikai Xiahou
- Jie Wang (ORCID: https://orcid.org/0000-0002-4673-9025)
- Zhou Sun (ORCID: https://orcid.org/0009-0000-2428-9679)
- Zhenzhen Zhao
- Chen Ding (ORCID: https://orcid.org/0000-0003-0013-3439)
- Jiqiang Niu
- Dongyang Zeng
Institutions
- Union Hospital (HK)
- Shandong University of Traditional Chinese Medicine (CN)
- Hubei University of Arts and Science (CN)
- Union Hospital (CN)
- Beijing Sport University (CN)
Publication Details
- Journal
- Translational Oncology
- Published
- 2024-12-24
- DOI
- https://doi.org/10.1016/j.tranon.2024.102255
- Citations
- 18
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 4.33