Non-V600E <i>BRAF</i> mutations and treatment for hairy cell leukemia
We found 20 patients with an immunophenotype consistent with classic hairy cell leukemia and BRAF mutations other than just V600E. Fourteen had 1 non-V600E BRAF mutation and 6 had V600E with 1 (n = 5) or 2 (n = 1) non-V600E BRAF comutations. This study was registered at https://clinicaltrials.gov as #NCT01087333.
Authors
- Chi‐Ping Day (ORCID: https://orcid.org/0000-0001-5200-2372)
- Yuelin Liu (ORCID: https://orcid.org/0000-0002-1051-7236)
- Constance M. Yuan (ORCID: https://orcid.org/0000-0002-2601-3665)
- Mark Raffeld (ORCID: https://orcid.org/0000-0002-4039-6957)
- Liqiang Xi (ORCID: https://orcid.org/0000-0001-5033-7072)
- Kerry Anne Rogers (ORCID: https://orcid.org/0000-0001-5748-7874)
- Seema Ali Bhat (ORCID: https://orcid.org/0000-0001-7844-0856)
- Evgeny Arons (ORCID: https://orcid.org/0000-0002-0792-7824)
- Chin‐Hsien Tai (ORCID: https://orcid.org/0000-0003-4766-0535)
- Hao‐Wei Wang (ORCID: https://orcid.org/0000-0002-5408-9253)
- Daniel Jones (ORCID: https://orcid.org/0000-0001-8108-0169)
- M N Gould (ORCID: https://orcid.org/0009-0009-4068-1561)
- Isaac Shpilman
- Michael R. Grever
- R. J. Kreitman
- Joshi Suraj (ORCID: https://orcid.org/0000-0002-2556-9194)
Institutions
- National Institutes of Health (US)
- National Cancer Institute (US)
- The Ohio State University (US)
- University of Maryland, College Park (US)
Publication Details
- Journal
- Blood
- Published
- 2024-12-24
- DOI
- https://doi.org/10.1182/blood.2024026894
- Citations
- 8
- Primary Topic
- Chronic Lymphocytic Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 3.50