STEAP4 with copper reductase activity suppresses tumorigenesis by regulating the cell cycle in hepatocellular carcinoma cells
Our results lay a foundation for further study of the cell cycle regulatory role of STEAP4 with Cu<sup>2+</sup> reductase activity in HCC, indicating that STEAP4 may be a promising therapeutic target for HCC.
Authors
- Shihai Jiang (ORCID: https://orcid.org/0000-0002-0559-6160)
- Ting Yang (ORCID: https://orcid.org/0000-0002-8182-0195)
- Qiong Zou (ORCID: https://orcid.org/0000-0001-6308-2259)
- Kun Wang (ORCID: https://orcid.org/0000-0003-1396-6325)
- Yong Zhang (ORCID: https://orcid.org/0000-0003-4041-6070)
- Yujie Xie (ORCID: https://orcid.org/0000-0002-2260-9242)
- Mengting Zou (ORCID: https://orcid.org/0009-0002-1278-4781)
Institutions
- Sun Yat-sen University (CN)
- University Hospital Leipzig (DE)
- Third Affiliated Hospital of Sun Yat-sen University (CN)
Publication Details
- Journal
- Cell Division
- Published
- 2024-12-24
- DOI
- https://doi.org/10.1186/s13008-024-00140-y
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Science Foundation
- Sun Yat-sen University
- Guangzhou Municipal Science and Technology Project
- Science and Technology Planning Project of Guangdong Province