PD-L1 expression in PitNETs: Correlations with the 2022 WHO classification
PD-L1 expression was associated with PIT-1 lineage, while it was downregulated in SF-1-lineage tumors. No correlation was found with proliferative factors. The role of PD-L1 expression in determining the biological behavior of PitNET remains debated and larger studies are necessary to further confirm these findings.
Authors
- Ethan Harel
- Jean‐Philippe Brouland (ORCID: https://orcid.org/0000-0003-3475-0101)
- Nelly Pitteloud (ORCID: https://orcid.org/0000-0003-0971-3237)
- Maxime Brunner
- Giulia Cossu (ORCID: https://orcid.org/0000-0003-0913-8965)
- Stefano La Rosa (ORCID: https://orcid.org/0000-0003-1941-2403)
- Mahmoud Messerer (ORCID: https://orcid.org/0000-0003-4975-8237)
- Roy Thomas Daniel (ORCID: https://orcid.org/0000-0002-7079-9837)
- Federico Santoni (ORCID: https://orcid.org/0000-0002-3258-4747)
- Ekkehard Hewer (ORCID: https://orcid.org/0000-0002-9128-0364)
Institutions
- University of Insubria (IT)
- University of Lausanne (CH)
Publication Details
- Journal
- Brain and Spine
- Published
- 2024-12-24
- DOI
- https://doi.org/10.1016/j.bas.2024.104171
- Citations
- 1
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.28