Etiopathogenetic Features of Dermatomycosis in HIV- Infected Patients

the review of current literary sources is aimed at the analysis of data on the etiopathogenetic features of dermatomycosis in HIV-infected patients, because the course of these diseases in HIV-infected patients needs more attention. Depending on the key mechanisms of development of immunosuppression, two main groups of fungal diseases are distinguished. The first group includes mycoses associated with the predominance of quantitative and qualitative neutrophil lesions; to the second - with defects in cell-mediated immunity. Mycoses are among the most common opportunistic diseases that occur in HIV-infected patients. Pneumocystis carinii, Candida albicans and Cryptococcus neoformans in HIV infection are the main causative agents of mycoses, especially in the stage of AIDS. Mycoses are early clinical manifestations of HIV infection, and oropharyngeal candidiasis is one of the most common opportunistic diseases. The developed form of oropharyngeal candidiasis against the background of the absence of favorable factors allows one to suspect HIV infection for the first time and has an important prognostic value for assessing the further course of the underlying disease. At the same time, it is worth paying attention to the fact that the incidence of dermatoses is caused by a wide range of pathogens, the basis of which is a complex and not fully understood multicomponent system of pathogenesis.

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Publication Details

Journal
Ukrainian Scientific Medical Youth Journal
Published
2024-12-23
DOI
https://doi.org/10.32345/usmyj.4(150).2024.60-68
Primary Topic
Nail Diseases and Treatments
Type
article
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Etiopathogenetic Features of Dermatomycosis in HIV- Infected Patients

И. И. Кравчук
Ukrainian Scientific Medical Youth Journal
Nail Diseases and Treatments
article

Etiopathogenetic Features of Dermatomycosis in HIV- Infected Patients

И. И. Кравчук
article en

Abstract

the review of current literary sources is aimed at the analysis of data on the etiopathogenetic features of dermatomycosis in HIV-infected patients, because the course of these diseases in HIV-infected patients needs more attention. Depending on the key mechanisms of development of immunosuppression, two main groups of fungal diseases are distinguished. The first group includes mycoses associated with the predominance of quantitative and qualitative neutrophil lesions; to the second - with defects in cell-mediated immunity. Mycoses are among the most common opportunistic diseases that occur in HIV-infected patients. Pneumocystis carinii, Candida albicans and Cryptococcus neoformans in HIV infection are the main causative agents of mycoses, especially in the stage of AIDS. Mycoses are early clinical manifestations of HIV infection, and oropharyngeal candidiasis is one of the most common opportunistic diseases. The developed form of oropharyngeal candidiasis against the background of the absence of favorable factors allows one to suspect HIV infection for the first time and has an important prognostic value for assessing the further course of the underlying disease. At the same time, it is worth paying attention to the fact that the incidence of dermatoses is caused by a wide range of pathogens, the basis of which is a complex and not fully understood multicomponent system of pathogenesis.

Ukrainian Scientific Medical Youth JournalVol. 150(4)
Bukovinian State Medical University (UA)
Good health and well-being
Openalex Percentile: Top 64%
Nail Diseases and Treatments
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Etiopathogenetic Features of Dermatomycosis in HIV- Infected Patients — И. И. Кравчук · Ukrainian Scientific Medical Youth Journal (2024) | TGRS Research Map | TGRS