Review: Haloperidol, fluphenazine, clozapine show poor results on cognition

A systematic review and network meta‐analysis encompassing 68 randomized trials has concluded that the antipsychotics haloperidol, fluphenazine, and clozapine ranked lowest on measures of cognition in patients with schizophrenia and related disorders. There were few clear differences overall among the antipsychotics studied, the investigators reported. Results were published online Oct. 16, 2024, in JAMA Psychiatry .

Publication Details

Journal
The Brown University Psychopharmacology Update
Published
2024-12-24
DOI
https://doi.org/10.1002/pu.31261
Primary Topic
Schizophrenia research and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Review: Haloperidol, fluphenazine, clozapine show poor results on cognition

The Brown University Psychopharmacology Update
Schizophrenia research and treatment
article

Review: Haloperidol, fluphenazine, clozapine show poor results on cognition

article en

Abstract

A systematic review and network meta‐analysis encompassing 68 randomized trials has concluded that the antipsychotics haloperidol, fluphenazine, and clozapine ranked lowest on measures of cognition in patients with schizophrenia and related disorders. There were few clear differences overall among the antipsychotics studied, the investigators reported. Results were published online Oct. 16, 2024, in JAMA Psychiatry .

The Brown University Psychopharmacology UpdateVol. 36(2)
No poverty
Openalex Percentile: Top 67%
Schizophrenia research and treatment
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Review: Haloperidol, fluphenazine, clozapine show poor results on cognition · The Brown University Psychopharmacology Update (2024) | TGRS Research Map | TGRS