Synthesis, spectral characterization and antibacterial activities of Schiff base derived from 3-hydroxybenzofuran-2-carbaldehyde and (furan-2-yl)methanamine and its metal complexes

We have synthesized a Schiff base, 2-((E)-((furan-2-yl)methylimino)methyl)benzofuran-3-ol and assessed it using elemental analyses, infrared spectroscopy, nuclear magnetic resonance, mass spectra and thermal analysis (TGA). The complexes' analytical results confirm the synthesis of a 1:2 [M:L] ratio of the formula [ML2], where M corresponds to the ions Cu(II), Ni(II), Zn(II), Mn(II) and L for the deprotonated Schiff base. Metal ions are bidentately coupled to Schiff base via azomethine-N and phenolic-oxygen groups, according to infrared spectra. The disc diffusion technique was used to test the ligand and their metal chelates for their antibacterial properties against the specified microorganisms.

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Publication Details

Journal
Indian Journal of Chemistry
Published
2024-12-24
DOI
https://doi.org/10.56042/ijc.v63i12.13135
Primary Topic
Metal complexes synthesis and properties
Type
article
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article

Synthesis, spectral characterization and antibacterial activities of Schiff base derived from 3-hydroxybenzofuran-2-carbaldehyde and (furan-2-yl)methanamine and its metal complexes

Indian Journal of Chemistry
Metal complexes synthesis and properties
article

Synthesis, spectral characterization and antibacterial activities of Schiff base derived from 3-hydroxybenzofuran-2-carbaldehyde and (furan-2-yl)methanamine and its metal complexes

article en

Abstract

We have synthesized a Schiff base, 2-((E)-((furan-2-yl)methylimino)methyl)benzofuran-3-ol and assessed it using elemental analyses, infrared spectroscopy, nuclear magnetic resonance, mass spectra and thermal analysis (TGA). The complexes' analytical results confirm the synthesis of a 1:2 [M:L] ratio of the formula [ML2], where M corresponds to the ions Cu(II), Ni(II), Zn(II), Mn(II) and L for the deprotonated Schiff base. Metal ions are bidentately coupled to Schiff base via azomethine-N and phenolic-oxygen groups, according to infrared spectra. The disc diffusion technique was used to test the ligand and their metal chelates for their antibacterial properties against the specified microorganisms.

Indian Journal of ChemistryVol. 63(12)
Kakatiya University (IN)
Clean water and sanitation
Openalex Percentile: Top 59%
Metal complexes synthesis and properties
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