Long‐term outcome of pediatric acute severe colitis: A prospective 5‐year follow‐up of the PRASCO trial

While adding antibiotics to IVCS may provide better short-term outcomes, the long-term benefits were comparable to IVCS alone. At 5 years, about one-fifth of children had undergone colectomy, and almost four-fifths had escalated to biologics, particularly during the first year after admission.

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Publication Details

Journal
Journal of Pediatric Gastroenterology and Nutrition
Published
2024-12-24
DOI
https://doi.org/10.1002/jpn3.12442
Primary Topic
Inflammatory Bowel Disease
Type
article
Field-Weighted Citation Impact
0.00

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article

Long‐term outcome of pediatric acute severe colitis: A prospective 5‐year follow‐up of the PRASCO trial

Esther Orlanski‐Meyer, Amit Assa, Kaija‐Leena Kolho, Baruch Yerushalmi et al.
Journal of Pediatric Gastroenterology and Nutrition
Inflammatory Bowel Disease
article

Long‐term outcome of pediatric acute severe colitis: A prospective 5‐year follow‐up of the PRASCO trial

Esther Orlanski‐Meyer, Amit Assa, Kaija‐Leena Kolho, Baruch Yerushalmi, Ohad Atia, Anne M. Griffiths, Itzhak Bar‐Or, Oren Ledder, Raffi Lev‐Tzion, Shlomi Cohen, Dan Turner, Lindsey Albenberg, Z Shavit-Brunschwig, Dror S. Shouval, M Aloi, Dan Lachman
article en

Abstract

While adding antibiotics to IVCS may provide better short-term outcomes, the long-term benefits were comparable to IVCS alone. At 5 years, about one-fifth of children had undergone colectomy, and almost four-fifths had escalated to biologics, particularly during the first year after admission.

Journal of Pediatric Gastroenterology and NutritionVol. 80(3)
Ben-Gurion University of the Negev (IL), Children's Hospital of Philadelphia (US), Tel Aviv University (IL), Hebrew University of Jerusalem (IL), Tel Aviv Sourasky Medical Center (IL), Wolfson Medical Center (IL), Shaare Zedek Medical Center (IL), Helsinki Children's Hospital (FI), Schneider Children's Medical Center (IL), SickKids Foundation (CA), Sapienza University of Rome (IT)
Leona M. and Harry B. Helmsley Charitable Trust, Hebrew University of Jerusalem
Good health and well-being
Openalex Percentile: Top 74%
Inflammatory Bowel Disease
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Long‐term outcome of pediatric acute severe colitis: A prospective 5‐year follow‐up of the PRASCO trial — Esther Orlanski‐Meyer, Amit Assa, et al. · Journal of Pediatric Gastroenterology and Nutrition (2024) | TGRS Research Map | TGRS