Clinical Practice Guidelines for the Management of Congenital Syphilis in Japan, 2023: Executive Summary

Congenital syphilis (CS) is a mother-to-child infection caused by the bacterium Treponema pallidum , transmitted through the placenta. In Japan, the number of syphilis cases has recently increased, accompanied by an increase in CS cases. Thus, automated methods for serum antibodies with serial values, without a 2× dilution sequence, have been widely used. Moreover, benzathine penicillin G was introduced in Japan in 2021. In response to the recent surge in CS, the first edition of the clinical practice guidelines for the management of CS was developed by a committee comprising representatives from 4 Japanese medical societies. This summary outlines 5 clinical questions with statements and expert comments regarding diagnosis, treatment and follow-up requirements. These guidelines aim to assist in the management of patients with CS infection.

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Publication Details

Journal
The Pediatric Infectious Disease Journal
Published
2024-12-20
DOI
https://doi.org/10.1097/inf.0000000000004665
Citations
3
Primary Topic
Syphilis Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.98
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article

Clinical Practice Guidelines for the Management of Congenital Syphilis in Japan, 2023: Executive Summary

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3 citations
The Pediatric Infectious Disease Journal
Syphilis Diagnosis and Treatment
0.98
article

Clinical Practice Guidelines for the Management of Congenital Syphilis in Japan, 2023: Executive Summary

Yuka Yamagishi, Masayoshi Shinjoh, Chiaki Ikenoue, Noriko Takeuchi, Takuya Yamagishi, Hiroyuki Moriuchi, Kei Kawana, Munehiro Furuichi, Isao Miyairi, Masaaki Mori, Naruhiko Ishiwada, Takeshi Tsugawa, Yoshinori Ito, Ichiro Morioka, Sota Iwatani, Takanori Funaki, Hiroyuki Shimizu, Kenta Ito, Kazunobu Ouchi, Hiroshige Mikamo, Tadashi Hoshino
article en
3 citations

Abstract

Congenital syphilis (CS) is a mother-to-child infection caused by the bacterium Treponema pallidum , transmitted through the placenta. In Japan, the number of syphilis cases has recently increased, accompanied by an increase in CS cases. Thus, automated methods for serum antibodies with serial values, without a 2× dilution sequence, have been widely used. Moreover, benzathine penicillin G was introduced in Japan in 2021. In response to the recent surge in CS, the first edition of the clinical practice guidelines for the management of CS was developed by a committee comprising representatives from 4 Japanese medical societies. This summary outlines 5 clinical questions with statements and expert comments regarding diagnosis, treatment and follow-up requirements. These guidelines aim to assist in the management of patients with CS infection.

The Pediatric Infectious Disease JournalVol. 44(3)
Japan Pediatric Society (JP)
Good health and well-being
Openalex Percentile: Top 22%
Syphilis Diagnosis and Treatment
0.98
DOISourceOpenAlex
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