Reprogramming tumor-associated macrophages with lipid nanosystems reduces PDAC tumor burden and liver metastasis

The demonstrated effectiveness and safety of our nanosystem therapy highlights a promising therapeutic approach for PDAC, showcasing its potential in reprogramming TAMs and mitigating the occurrence of liver metastasis.

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Publication Details

Journal
Journal of Nanobiotechnology
Published
2024-12-24
DOI
https://doi.org/10.1186/s12951-024-03010-5
Citations
6
Primary Topic
Immune cells in cancer
Type
article
Field-Weighted Citation Impact
1.44

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article

Reprogramming tumor-associated macrophages with lipid nanosystems reduces PDAC tumor burden and liver metastasis

Adrián Palencia‐Campos, Diego Navarro, Sonia Alcalá, Laura Sánchez et al.
6 citations
Journal of Nanobiotechnology
Immune cells in cancer
1.44
article

Reprogramming tumor-associated macrophages with lipid nanosystems reduces PDAC tumor burden and liver metastasis

Adrián Palencia‐Campos, Diego Navarro, Sonia Alcalá, Laura Sánchez, Bruno Sáinz, Simona Mura, Nadège Bidan, Laura Ruíz-Cañas, Juan A. Rubiolo, Juan Carlos López-Gil, Sofia M. Saraiva, Patrick Hermann, María de la Fuente, Balbino Yagüe, Sandra Batres-Ramos, Marcelina Abal-Sanisidro
article en
6 citations

Abstract

The demonstrated effectiveness and safety of our nanosystem therapy highlights a promising therapeutic approach for PDAC, showcasing its potential in reprogramming TAMs and mitigating the occurrence of liver metastasis.

Journal of NanobiotechnologyVol. 22(1)
Centre National de la Recherche Scientifique (FR), Universität Ulm (DE), Universidade de Santiago de Compostela (ES), Université Paris-Saclay (FR), Instituto de Salud Carlos III (ES), National University of Rosario (AR), Instituto de Investigaciones Biomédicas Sols-Morreale (ES), Instituto Ramón y Cajal de Investigación Sanitaria (ES), Complexo Hospitalario Universitario A Coruña (ES), Centro de Investigación Biomédica en Red de Cáncer (ES), Hospital Universitario Ramón y Cajal (ES), Universidad Autónoma de Madrid (ES)
“la Caixa” Foundation, Comunidad de Madrid, EuroNanoMed III, Universidad Autónoma de Madrid, Deutsche Krebshilfe, Consejo Superior de Investigaciones Científicas, Instituto de Salud Carlos III, European Regional Development Fund, H2020 European Research Council
Good health and well-being
Openalex Percentile: Top 17%
Immune cells in cancer
1.44
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