Tumor to triumph: bone reconstruction with extracorporeal irradiation in malignant bone tumors

Malignant bone tumors (MBTs) are predominantly seen in children and adolescents and account for <1% of diagnosed cancers each year. This case study demonstrates how ECI acts as a limb salvage method for MBT, particularly in low-income settings. A 17yr old male patient present pain & swelling around left ankle for 1 year. The radiograph showed lytic lesion in the left distal fibula followed by biopsy suggestive of osteosarcoma. Patient underwent four cycle of Adriyamycin based chemotherapy followed by wide local excision with extracorporeal irradiation. The patient also received four cycles of adjuvant chemotherapy. Now, patient was free of disease and on regular follow-up. By delivering high-dose radiation directly to affected bone ECI helps to minimize damage to surrounding healthy areas. It also offers significant therapeutic advantages, including enhanced tumor control and the preservation of limb functionality. As technology and techniques continue to evolve, ECI may play an important role in treating cancers that are challenging to manage with conventional therapies.

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Publication Details

Journal
Indian Journal of Orthopaedics Surgery
Published
2024-12-15
DOI
https://doi.org/10.18231/j.ijos.2024.064
Primary Topic
Bone Tumor Diagnosis and Treatments
Type
article
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article

Tumor to triumph: bone reconstruction with extracorporeal irradiation in malignant bone tumors

Saurabh Bhatia, Hanuman Prasad Sharma, Kushal Rawal
Indian Journal of Orthopaedics Surgery
Bone Tumor Diagnosis and Treatments
article

Tumor to triumph: bone reconstruction with extracorporeal irradiation in malignant bone tumors

Saurabh Bhatia, Hanuman Prasad Sharma, Kushal Rawal
article en

Abstract

Malignant bone tumors (MBTs) are predominantly seen in children and adolescents and account for <1% of diagnosed cancers each year. This case study demonstrates how ECI acts as a limb salvage method for MBT, particularly in low-income settings. A 17yr old male patient present pain & swelling around left ankle for 1 year. The radiograph showed lytic lesion in the left distal fibula followed by biopsy suggestive of osteosarcoma. Patient underwent four cycle of Adriyamycin based chemotherapy followed by wide local excision with extracorporeal irradiation. The patient also received four cycles of adjuvant chemotherapy. Now, patient was free of disease and on regular follow-up. By delivering high-dose radiation directly to affected bone ECI helps to minimize damage to surrounding healthy areas. It also offers significant therapeutic advantages, including enhanced tumor control and the preservation of limb functionality. As technology and techniques continue to evolve, ECI may play an important role in treating cancers that are challenging to manage with conventional therapies.

Indian Journal of Orthopaedics SurgeryVol. 10(4)
King George's Medical University (IN), All India Institute of Medical Sciences Rishikesh (IN), All India Institute of Medical Sciences (IN)
No poverty
Openalex Percentile: Top 59%
Bone Tumor Diagnosis and Treatments
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Tumor to triumph: bone reconstruction with extracorporeal irradiation in malignant bone tumors — Saurabh Bhatia, Hanuman Prasad Sharma, et al. · Indian Journal of Orthopaedics Surgery (2024) | TGRS Research Map | TGRS