CYBC1 Drives Glioblastoma Progression via Reactive Oxygen Species and NF-κB Pathways
CYBC1 is implicated in GBM progression by regulating NOXA1-mediated ROS production and activating the ERK·AKT/NF-κB pathways. This study suggests that CYBC1 could serve as a potential therapeutic target and prognostic marker in GBM, warranting further investigation into its molecular mechanisms and therapeutic potential.
Authors
- Jin‐Hwa Cho
- Jin‐Seok Byun (ORCID: https://orcid.org/0000-0002-6182-1238)
- Mee-Seon Kim
- Do‐Yeon Kim (ORCID: https://orcid.org/0000-0003-2200-7396)
- Hyeon Ji Kim (ORCID: https://orcid.org/0000-0003-0483-5438)
- Tae‐Jun Kim (ORCID: https://orcid.org/0000-0003-1991-995X)
Institutions
- Kyungpook National University (KR)
Publication Details
- Journal
- Cancer Research and Treatment
- Published
- 2024-12-24
- DOI
- https://doi.org/10.4143/crt.2024.827
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Research Foundation
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea