STZ-induced hyperglycemia differentially influences mitochondrial distribution and morphology in the habenulointerpeduncular circuit
This study is the first to describe the specific impacts of diabetes on mitochondria in the MHb-IPN circuit and suggests that the cholinergic MHb is uniquely sensitive to diabetesinduced hyperglycemia. Further studies are needed to understand the functional and behavioral implications of these findings.
Authors
- T. Matos
- Kristi Niblo
- Mohammad Jodeiri Farshbaf (ORCID: https://orcid.org/0000-0001-5254-6572)
- Jessica L. Ables (ORCID: https://orcid.org/0000-0003-1818-3506)
- Yacoub Alokam
Institutions
- Allen Institute for Brain Science (US)
- St. Francis College (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Frontiers in Cellular Neuroscience
- Published
- 2024-12-23
- DOI
- https://doi.org/10.3389/fncel.2024.1432887
- Primary Topic
- Mitochondrial Function and Pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Brain and Behavior Research Foundation