Sex and <i>APOE</i> ε4 allele differences in longitudinal white matter microstructure in multiple cohorts of aging and Alzheimer's disease

Sex and apolipoprotein E (APOE) ε4 carrier status relate to white matter microstructural integrity. Females generally have lower free water-corrected fractional anisotropy compared to males. APOE ε4 carriers tended to have higher free water than non-carriers.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2024-12-22
DOI
https://doi.org/10.1002/alz.14343
Citations
11
Primary Topic
Advanced Neuroimaging Techniques and Applications
Type
article
Field-Weighted Citation Impact
4.45

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article

Sex and APOE ε4 allele differences in longitudinal white matter microstructure in multiple cohorts of aging and Alzheimer's disease

Susan M. Resnick, Timothy J. Hohman, Arthur W. Toga, Niranjana Shashikumar et al.
11 citations
Alzheimer s & Dementia
Advanced Neuroimaging Techniques and Applications
4.45
article

Sex and APOE ε4 allele differences in longitudinal white matter microstructure in multiple cohorts of aging and Alzheimer's disease

Susan M. Resnick, Timothy J. Hohman, Arthur W. Toga, Niranjana Shashikumar, Sarah Biber, Shannon L. Risacher, Chenyu Gao, Julie A. Schneider, Mohamad Habes, Andrew J. Saykin, Lisa L. Barnes, Derek B. Archer, Logan C. Dumitrescu, Amalia Jo Peterson, Di Wang, Christos A. Davatzikos, Kacie Deters, Lori L. Beason‐Held, Guray Erus, Konstantinos Arfanakis, Kurt G. Schilling, Walter A. Kukull, Michael E. Kim, Tianyuan Yao, Angela Lee Jefferson, Yuankai Huo, Kimberly R. Pechman, Bennett A. Landman, Duygu Tosun, Elizabeth C. Mormino, Francis E. Cambronero, Jo Ellen Wilson, Alaina Durant, Dimitrios Zaras, Zhiyuan Li, Panpan Zhang, Yang An, Paul M. Thompson, Marilyn Albert, Nazirah Mohd Khairi, Katherine A. Gifford, Sterling C. Johnson, David A. Bennett, Aditi Sathe, Yisu Yang
article en
11 citations

Abstract

Sex and apolipoprotein E (APOE) ε4 carrier status relate to white matter microstructural integrity. Females generally have lower free water-corrected fractional anisotropy compared to males. APOE ε4 carriers tended to have higher free water than non-carriers.

Alzheimer s & DementiaVol. 21(1)
University of Southern California (US), Rush University Medical Center (US), National Institutes of Health (US), University of Wisconsin–Madison (US), Johns Hopkins University (US), University of California, Los Angeles (US), The University of Texas at San Antonio Health Science Center (US), University of California, San Francisco (US), Illinois Institute of Technology (US), Vanderbilt University (US), University of Washington (US), University of California System (US), VA Tennessee Valley Healthcare System (US), Geriatric Research Education and Clinical Center (US), Institute for Neurodegenerative Disorders (US), National Institute on Aging (US), Indiana University School of Medicine, Indiana University – Purdue University Indianapolis (US), University of Pennsylvania (US), Vanderbilt University Medical Center (US), Stanford University (US)
Alzheimer's Association, Vanderbilt University, Vanderbilt Memory and Alzheimer's Center, Vanderbilt University Medical Center, National Institutes of Health, National Institute on Aging
Clean water and sanitation
Openalex Percentile: Top 5%
Advanced Neuroimaging Techniques and Applications
4.45
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