Role of PARK7/DJ-1 in Gastrointestinal Diseases

Parkinson’s disease 7 (PARK7/DJ-1) is an evolutionarily conserved multifunctional protein whose role has been widely demonstrated in malignant tumours and neurodegenerative diseases, including Parkinson's or Alzheimer's disease. However, recent studies also revealed protective role of PARK7/DJ-1 regarding gastrointestinal diseases. In the present review, we discuss our current knowledge about PARK7/DJ-1 in the context of coeliac and inflammatory bowel disease.

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Publication Details

Journal
International Journal of Celiac Disease
Published
2024-12-22
DOI
https://doi.org/10.12691/ijcd-12-1-6
Primary Topic
Helicobacter pylori-related gastroenterology studies
Type
article
Field-Weighted Citation Impact
0.00

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Role of PARK7/DJ-1 in Gastrointestinal Diseases

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Role of PARK7/DJ-1 in Gastrointestinal Diseases

Domonkos Pap, Csenge Szász, Beáta Szebeni, Ádám Vannay, Apor Veres-Székely, Péter Bokrossy, Zrufkó Réka
article en

Abstract

Parkinson’s disease 7 (PARK7/DJ-1) is an evolutionarily conserved multifunctional protein whose role has been widely demonstrated in malignant tumours and neurodegenerative diseases, including Parkinson's or Alzheimer's disease. However, recent studies also revealed protective role of PARK7/DJ-1 regarding gastrointestinal diseases. In the present review, we discuss our current knowledge about PARK7/DJ-1 in the context of coeliac and inflammatory bowel disease.

International Journal of Celiac DiseaseVol. 12(1)
Semmelweis Egyetem, Magyar Tudományos Akadémia, Nemzeti Kutatási Fejlesztési és Innovációs Hivatal, Nemzeti Kutatási, Fejlesztési és Innovaciós Alap, National Research, Development and Innovation Office
Zero hunger
Openalex Percentile: Top 56%
Helicobacter pylori-related gastroenterology studies
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