Siesta behavior and genetics interact to influence obesity risk

A total of 42.4% of the population usually took siesta. A significant genetic influence on siesta propensity was found, with a higher genetic predisposition linked to taking siesta more frequently (odds ratio [OR] = 1.17, 95% CI: 1.03-1.32; p = 0.015). Participants with a higher genetic propensity for siesta showed poorer dietary habits (p < 0.05). Among individuals with a high genetic propensity for siesta, we found that those who usually take siesta have lower odds of having obesity (p = 0.038) compared with those who do not. Similarly, in exploratory analysis, among individuals with a high genetic propensity for siesta, we found that those who usually take siesta have higher odds of weight-loss success (p = 0.007) compared with those who do not. CONCLUSIONS: Considering the ongoing debate regarding whether siesta is beneficial or detrimental, our findings suggest that individual genetic predisposition to siesta might influence the association between siesta and health.

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Publication Details

Journal
Obesity
Published
2024-12-23
DOI
https://doi.org/10.1002/oby.24173
Citations
2
Primary Topic
Obesity, Physical Activity, Diet
Type
article
Field-Weighted Citation Impact
1.09

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article

Siesta behavior and genetics interact to influence obesity risk

Aurora Aragón Alonso, Ana Isabel Cascales, Frank A. J. L. Scheer, Richa Saxena et al.
2 citations
Obesity
Obesity, Physical Activity, Diet
1.09
article

Siesta behavior and genetics interact to influence obesity risk

Aurora Aragón Alonso, Ana Isabel Cascales, Frank A. J. L. Scheer, Richa Saxena, Hassan S. Dashti, Diego Salmerón, María Rodríguez‐Martín, Marta Garaulet
article en
2 citations

Abstract

A total of 42.4% of the population usually took siesta. A significant genetic influence on siesta propensity was found, with a higher genetic predisposition linked to taking siesta more frequently (odds ratio [OR] = 1.17, 95% CI: 1.03-1.32; p = 0.015). Participants with a higher genetic propensity for siesta showed poorer dietary habits (p < 0.05). Among individuals with a high genetic propensity for siesta, we found that those who usually take siesta have lower odds of having obesity (p = 0.038) compared with those who do not. Similarly, in exploratory analysis, among individuals with a high genetic propensity for siesta, we found that those who usually take siesta have higher odds of weight-loss success (p = 0.007) compared with those who do not. CONCLUSIONS: Considering the ongoing debate regarding whether siesta is beneficial or detrimental, our findings suggest that individual genetic predisposition to siesta might influence the association between siesta and health.

ObesityVol. 33(1)
Broad Institute (US), Brigham and Women's Hospital (US), Harvard University (US), Massachusetts General Hospital (US), Circadian (United States) (US), Hospital Universitario Virgen de la Arrixaca (ES), Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (ES), Universidad de Murcia (ES)
Ministerio de Ciencia e Innovación, National Institutes of Health, Agencia Estatal de Investigación
No poverty
Openalex Percentile: Top 19%
Obesity, Physical Activity, Diet
1.09
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