Ethyl 4-[(2-hydroxyethyl)amino]-2-(4-methoxyphenyl)-1-methyl-5-oxo-2,5-dihydro-1<i>H</i>-pyrrole-3-carboxylate

In the title compound, C<sub>17</sub>H<sub>22</sub>N<sub>2</sub>O<sub>5</sub> the pyrrolidine ring is almost planar and subtends a dihedral angle of 85.77 (7)° with the pendant phenyl ring. An intra-molecular N-H⋯O hydrogen bond generates an <i>S</i>(6) loop. In the crystal, the compound forms inversion dimers through O-H⋯O hydrogen bonds from the disordered hydroxyl group to either the hydroxyl or ester carbonyl O atom of the adjacent mol-ecule.

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IUCrData
Published
2024-12-20
DOI
https://doi.org/10.1107/s2414314624012227
Primary Topic
Crystal structures of chemical compounds
Type
article
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article

Ethyl 4-[(2-hydroxyethyl)amino]-2-(4-methoxyphenyl)-1-methyl-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylate

David B. Cordes, Aidan P. McKay, Mohd Fazli Mohammat, Fatin Nur Ain Abdul Rashid et al.
IUCrData
Crystal structures of chemical compounds
article

Ethyl 4-[(2-hydroxyethyl)amino]-2-(4-methoxyphenyl)-1-methyl-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylate

David B. Cordes, Aidan P. McKay, Mohd Fazli Mohammat, Fatin Nur Ain Abdul Rashid, Mohd Abdul Fatah Abdul Manan, Ayisy Amirul Afti Bakhtiar Afendy
article en

Abstract

In the title compound, C<sub>17</sub>H<sub>22</sub>N<sub>2</sub>O<sub>5</sub> the pyrrolidine ring is almost planar and subtends a dihedral angle of 85.77 (7)° with the pendant phenyl ring. An intra-molecular N-H⋯O hydrogen bond generates an <i>S</i>(6) loop. In the crystal, the compound forms inversion dimers through O-H⋯O hydrogen bonds from the disordered hydroxyl group to either the hydroxyl or ester carbonyl O atom of the adjacent mol-ecule.

IUCrDataVol. 9(12)
University of St Andrews (GB), Chemical Synthesis Lab (SG), Universiti Teknologi MARA (MY)
Universiti Teknologi MARA
Clean water and sanitation
Openalex Percentile: Top 81%
Crystal structures of chemical compounds
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