Clinical Impact of TP53 Mutations in Patients with Head and Neck Cancer Who Were Treated with Targeted Therapies or Immunotherapy

TP53 mutations were associated with aggressive clinical characteristics and poor survival, particularly in HNSCC patients treated with immunotherapy.

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Publication Details

Journal
Cancer Research and Treatment
Published
2024-12-23
DOI
https://doi.org/10.4143/crt.2024.836
Primary Topic
Cancer-related Molecular Pathways
Type
article
Field-Weighted Citation Impact
0.00

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article

Clinical Impact of TP53 Mutations in Patients with Head and Neck Cancer Who Were Treated with Targeted Therapies or Immunotherapy

Eun Joo Kang, Yun‐Gyoo Lee, Seong Hoon Shin, Yoon Hee Choi et al.
Cancer Research and Treatment
Cancer-related Molecular Pathways
article

Clinical Impact of TP53 Mutations in Patients with Head and Neck Cancer Who Were Treated with Targeted Therapies or Immunotherapy

Eun Joo Kang, Yun‐Gyoo Lee, Seong Hoon Shin, Yoon Hee Choi, Sung‐Bae Kim, Hye Ryun Kim, Sang-Gon Park, Shinwon Hwang, Hwan‐Jung Yun, Keun‐Wook Lee, Sangwoo Kim, Hyun Woo Lee, Min Kyoung Kim, Jong-Kwon Choi, Seung Taek Lim
article en

Abstract

TP53 mutations were associated with aggressive clinical characteristics and poor survival, particularly in HNSCC patients treated with immunotherapy.

Cancer Research and TreatmentVol. 57(3)
Ulsan College (KR), Yonsei University (KR), Korea University (KR), Korea University Medical Center (KR), Kosin University Gospel Hospital (KR), Asan Medical Center (KR), New Generation University College (ET), Seoul National University Bundang Hospital (KR), University of Ulsan (KR), Chosun University Hospital (KR), Wonju Severance Christian Hospital (KR), Kangbuk Samsung Hospital (KR), Konyang University Hospital (KR), National University College (PR), Chungnam National University Hospital (KR), Dongnam Institute of Radiological & Medical Sciences (KR), Yeungnam University Medical Center (KR), Yeungnam University College, Yeungnam University (KR), Ajou University (KR), Sungkyunkwan University (KR)
National Research Foundation, Ministry of Science and ICT, South Korea
Good health and well-being
Openalex Percentile: Top 59%
Cancer-related Molecular Pathways
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