Cationic Hydroxyethyl Cellulose Nanocomplexes and RANK siRNA/Zoledronate Co-Delivery Systems for Osteoclast Inhibition
HECP2k/(RANK siRNA + Zol) nanocomplexes formed by simple mixing showed great potential for inhibiting osteoclast differentiation and osteoclast activity, inducing the apoptosis via combinatorial effects of RANK siRNA and Zol.
Authors
- Seoyeon Park (ORCID: https://orcid.org/0000-0002-0964-1467)
- SoHyun Lee (ORCID: https://orcid.org/0000-0001-9992-6038)
- Tae‐il Kim (ORCID: https://orcid.org/0000-0002-9355-7574)
Institutions
- Seoul National University (KR)
Publication Details
- Journal
- Pharmaceutics
- Published
- 2024-12-22
- DOI
- https://doi.org/10.3390/pharmaceutics16121623
- Primary Topic
- Bone Metabolism and Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Research Foundation
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea