Crystal structure and Hirshfeld surface analysis of <i>N</i>-(4-nitrophenyl)-2-(piperidin-1-yl)acetamide (lidocaine analogue)
In the title mol-ecule, C<sub>13</sub>H<sub>17</sub>N<sub>3</sub>O<sub>3</sub>, the substituents on the phenyl ring are rotated slightly out of the mean plane of the ring but the piperidine moiety is nearly perpendicular to that plane. In the crystal, C-H⋯O hydrogen bonds form chains of mol-ecules extending along the <i>c</i>-axis direction, which are linked by C=O⋯π(ring) inter-actions. A Hirshfeld surface analysis showed the majority of inter-molecular inter-actions to be H⋯H contacts while O⋯H/H⋯O contacts are the second most numerous.
Authors
- Intissar Nchioua
- Youssef Ramli (ORCID: https://orcid.org/0000-0002-6885-5692)
- Abderrazzak El Moutaouakil Ala Allah (ORCID: https://orcid.org/0000-0002-4846-4547)
- A. Zarrouk (ORCID: https://orcid.org/0000-0002-5495-2125)
- Benson M. Kariuki (ORCID: https://orcid.org/0000-0002-8658-3897)
- Joel T. Mague (ORCID: https://orcid.org/0000-0003-3488-1945)
- Abdulsalam Alsubari
- Imane Maimoune (ORCID: https://orcid.org/0009-0002-6019-3054)
Institutions
- Tulane University (US)
- Mohammed V University (MA)
- Cardiff University (GB)
Publication Details
- Journal
- Acta Crystallographica Section E Crystallographic Communications
- Published
- 2024-12-23
- DOI
- https://doi.org/10.1107/s205698902401185x
- Primary Topic
- Crystal structures of chemical compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Centre National pour la Recherche Scientifique et Technique