Identification of the whole genome of alternative splicing and RNA-binding proteins involved in nintedanib-induced apoptosis in gastric cancer cells
This study systematically identified important changes in alternative splicing and RNA-binding proteins during the process of nintedanib-induced apoptosis in gastric cancer cells. It innovatively revealed the mechanisms of action of nintedanib in gastric cancer cells and expanded the selection of new targets for gastric cancer treatment.
Authors
- Zhilong Liu (ORCID: https://orcid.org/0000-0002-7854-7642)
- Miao Yu (ORCID: https://orcid.org/0000-0002-8298-1679)
- Xiaohua Dong
- Xiaojun Yang (ORCID: https://orcid.org/0000-0001-9833-6415)
- Hui Cai
Institutions
- Gansu Provincial Hospital (CN)
- Lanzhou University (CN)
Publication Details
- Journal
- PeerJ
- Published
- 2024-12-23
- DOI
- https://doi.org/10.7717/peerj.18697
- Primary Topic
- RNA Research and Splicing
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Gansu Province
- National Health Commission of the People's Republic of China