Impact of liquid–liquid phase separation- and immune-related gene signatures on multiple myeloma prognosis: focus on DDX21 and EZH2
LLPS-related <i>EZH2</i> and <i>DDX21</i> were novel markers to predict prognostic risk of MM. Among them, <i>DDX21</i> was experimentally confirmed to promote MM cell proliferation, migration and invasion. These potential prognostic markers could be targeted in future personalized therapeutic strategies for MM, potentially improving patient outcomes.
Authors
- Fengming Wang (ORCID: https://orcid.org/0000-0001-5340-228X)
- Changxian Shen (ORCID: https://orcid.org/0000-0002-7668-7166)
Institutions
- Shaoxing People's Hospital (CN)
Publication Details
- Journal
- Hematology
- Published
- 2024-12-23
- DOI
- https://doi.org/10.1080/16078454.2024.2445403
- Citations
- 3
- Primary Topic
- RNA Research and Splicing
- Type
- article
- Field-Weighted Citation Impact
- 0.70