Changes in PD-1 expression on T lymphocyte subsets and related immune indicators before and after definitive chemoradiotherapy for esophageal squamous cell carcinoma
CRT aggravated immunosuppression and increased PD-1 expression in T lymphocyte subsets in patients with ESCC, possibly related to the radiation field. PD-1 expression in T lymphocyte subsets can predict short-term outcomes in patients and provide a theoretical basis for the sequential application of PD-1 immunosuppressants after radiotherapy and chemotherapy.
Authors
- Ning Yang
- Duojie Li
- Shixiang Zhou (ORCID: https://orcid.org/0000-0001-8784-3104)
- Zhao Hongyu (ORCID: https://orcid.org/0009-0003-1925-3403)
- Peng Cai (ORCID: https://orcid.org/0000-0002-5899-3952)
- Jiaqi Yu (ORCID: https://orcid.org/0009-0005-2118-128X)
- Xueling Shi (ORCID: https://orcid.org/0009-0005-5268-7259)
Institutions
- Bengbu Medical College (CN)
- First Affiliated Hospital of Bengbu Medical College (CN)
Publication Details
- Journal
- Annals of Medicine
- Published
- 2024-12-23
- DOI
- https://doi.org/10.1080/07853890.2024.2445190
- Citations
- 1
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.28
Funders
- Anhui University