Use of Polymerase Chain Reaction to Characterize the Etiology of Culture-Negative Empyema and Parapneumonic Effusion Among Alaska Native Children—2018-2023
We used polymerase chain reaction (PCR) to identify bacterial infections in culture-negative pleural fluid specimens from Alaska Native children hospitalized with empyema. PCR identified ≥1 organism in 11 (79%) of 14 specimens. Streptococcus pneumoniae serotype 3 was detected in 6 specimens; all 6 participants had received 13-valent pneumococcal conjugate vaccine.
Authors
- Jonathan Steinberg (ORCID: https://orcid.org/0000-0001-8446-5304)
- Benjamin Westley
- Srinivasan Velusamy
- Marc Fischer (ORCID: https://orcid.org/0009-0001-6394-3490)
- Marah Gotcsik
- Jesse Geis
- Carolynn DeByle (ORCID: https://orcid.org/0000-0003-2711-4588)
Institutions
- Centers for Disease Control and Prevention (US)
- Alaska Native Medical Center (US)
- Centers for Disease Control and Prevention (UG)
Publication Details
- Journal
- Journal of the Pediatric Infectious Diseases Society
- Published
- 2024-12-23
- DOI
- https://doi.org/10.1093/jpids/piae131
- Citations
- 1
- Primary Topic
- Pneumonia and Respiratory Infections
- Type
- article
- Field-Weighted Citation Impact
- 0.39
Funders
- Centers for Disease Control and Prevention