Non-toxic core–shell nanowires for <i>in vitro</i> extracellular vesicle scavenging
Extracellular vesicles (EVs) from cancer cells promote abnormal growth in normal cells, potentially leading to cancer proliferation. We developed a nanowire-based EV-elimination device that efficiently eliminated EVs without toxicity. This method restored normal growth in mammary gland cells cultured with breast adenocarcinoma-derived EVs containing medium treated with the device.
Authors
- Kunanon Chattrairat (ORCID: https://orcid.org/0000-0001-7587-6777)
- Yoshinobu Baba (ORCID: https://orcid.org/0000-0002-3025-2255)
- Takao Yasui (ORCID: https://orcid.org/0000-0003-0333-3559)
- Kazuki Nagashima (ORCID: https://orcid.org/0000-0003-0180-816X)
- Piyawan Paisrisarn (ORCID: https://orcid.org/0000-0002-1061-8766)
- Takeshi Yanagida (ORCID: https://orcid.org/0000-0003-4837-5701)
- Yuta Nakamura (ORCID: https://orcid.org/0000-0003-3564-7181)
Institutions
- Tokyo Institute of Technology (JP)
- Hokkaido University (JP)
- National Institutes for Quantum Science and Technology (JP)
- Nagoya University (JP)
- The University of Tokyo (JP)
Publication Details
- Journal
- Chemical Communications
- Published
- 2024-12-23
- DOI
- https://doi.org/10.1039/d4cc03767g
- Citations
- 1
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.23
Funders
- Japan Agency for Medical Research and Development
- New Energy and Industrial Technology Development Organization
- Japan Society for the Promotion of Science
- AIP Network Laboratory
- Moonshot Research and Development Program