Genomic Analysis of Talaromyces verruculosus SJ9: An Efficient Tetracycline-, Enrofloxacin-, and Tylosin-Degrading Fungus
Through the correlation analysis of the whole-genome data of <i>T. verruculosus</i> SJ9, we identified a number of genes capable of encoding antibiotic-degrading enzymes in its gene function annotation database. These antibiotic-related enzymes provide some evidence that <i>T. verruculosus</i> SJ9 can degrade fluoroquinolone antibiotics, tetracycline antibiotics, and macrolide antibiotics. In summary, the complete genome sequence of <i>T. verruculosus</i> SJ9 has now been published, and this resource constitutes a significant dataset that will inform forthcoming transcriptomic, proteomic, and metabolic investigations of this fungal species. In addition, genomic studies of other filamentous fungi can utilize it as a reference. Thanks to the discoveries made in this study, the future application of this fungus in industrial production will be more rapid.
Authors
- Xiaoqing Wu (ORCID: https://orcid.org/0000-0003-2651-6112)
- Susu Fan (ORCID: https://orcid.org/0009-0000-9948-0021)
- Jing Fu (ORCID: https://orcid.org/0000-0001-7961-0888)
- Yuan Yan Tang (ORCID: https://orcid.org/0000-0002-6887-130X)
- Fangyuan Zhou (ORCID: https://orcid.org/0000-0002-7603-2303)
- Xinjian Zhang (ORCID: https://orcid.org/0000-0002-5839-6197)
- Chi Zhang (ORCID: https://orcid.org/0000-0002-3554-8418)
Institutions
- Qilu University of Technology (CN)
- Shandong Academy of Sciences (CN)
Publication Details
- Journal
- Genes
- Published
- 2024-12-21
- DOI
- https://doi.org/10.3390/genes15121643
- Citations
- 3
- Primary Topic
- Microbial Natural Products and Biosynthesis
- Type
- article
- Field-Weighted Citation Impact
- 1.34
Funders
- National Natural Science Foundation of China