Blood-Based Biomarkers for Identifying Disease Activity in AQP4-IgG–Positive Neuromyelitis Optica Spectrum Disorder
This longitudinal cohort study established optimal timing and thresholds for sGFAP and sNfL, which were consistent in independent cohorts, supporting these biomarkers' effectiveness in distinguishing NMOSD attacks from remission.
Authors
- Natália Trombini Mendes (ORCID: https://orcid.org/0000-0001-7104-0382)
- Ana Beatriz Ayroza Galvão Ribeiro Gomes (ORCID: https://orcid.org/0000-0003-1657-6891)
- Dagoberto Callegaro (ORCID: https://orcid.org/0000-0003-0077-173X)
- Aline de Moura Brasil Matos (ORCID: https://orcid.org/0000-0002-1854-2575)
- Patrick Schindler (ORCID: https://orcid.org/0000-0002-8846-121X)
- Klemens Ruprecht (ORCID: https://orcid.org/0000-0003-1962-6014)
- Jens Kühle (ORCID: https://orcid.org/0000-0002-6963-8892)
- Friedemann Paul (ORCID: https://orcid.org/0000-0002-6378-0070)
- Vinícius Andreoli Schoeps (ORCID: https://orcid.org/0000-0001-8875-0567)
- Pascal Benkert (ORCID: https://orcid.org/0000-0001-6525-8174)
- Anne‐Katrin Pröbstel (ORCID: https://orcid.org/0000-0002-7748-1872)
- Su Hyun Kim (ORCID: https://orcid.org/0000-0003-4268-6437)
- Jung Bin Kim (ORCID: https://orcid.org/0000-0002-8013-9349)
- Dong-Eun Lee (ORCID: https://orcid.org/0000-0001-8525-7494)
- Ki Hoon Kim (ORCID: https://orcid.org/0000-0001-6428-061X)
- Samira Luisa dos Apóstolos-Pereira
- Jae-Won Hyun
- J.T. Lerner
Institutions
- University of Basel (CH)
- Max Delbrück Center (DE)
- University Hospital of Basel (CH)
- Humboldt-Universität zu Berlin (DE)
- National Cancer Center (KR)
- Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (BR)
- Freie Universität Berlin (DE)
- Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- JAMA Neurology
- Published
- 2024-12-23
- DOI
- https://doi.org/10.1001/jamaneurol.2024.4400
- Citations
- 10
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 4.25