Regulatory T cell expansion prevents retinal degeneration in type 2 diabetes
Treg modulation in T2D offers a promising therapeutic approach to prevent early stages of DR. This strategy focuses on reducing neuroinflammation and mitigating the associated neuronal, glial, and vascular degenerative changes characteristic of DR.
Authors
- Alerie Guzman de la Fuente (ORCID: https://orcid.org/0000-0001-8366-4969)
- Jose A. Gomez‐Sanchez (ORCID: https://orcid.org/0000-0002-6746-1800)
- Cristina Hernández (ORCID: https://orcid.org/0000-0002-3109-1721)
- Patricia Bogdanov
- Alan W. Stitt (ORCID: https://orcid.org/0000-0002-8647-9918)
- María Llorián‐Salvador (ORCID: https://orcid.org/0000-0002-1120-6579)
- Anna Duarri (ORCID: https://orcid.org/0000-0003-4075-5478)
- David A. Pérez-Martínez (ORCID: https://orcid.org/0000-0001-5587-0415)
- Anna Deàs-Just (ORCID: https://orcid.org/0000-0002-3129-6313)
- Marta García‐Ramírez (ORCID: https://orcid.org/0000-0003-4249-7177)
- Rafael Simó (ORCID: https://orcid.org/0000-0003-0475-3096)
- Miao Tang (ORCID: https://orcid.org/0000-0002-5980-6207)
- Anna Álvarez-Guaita
- Lorena Ramos-Pérez
Institutions
- Universitat Autònoma de Barcelona (ES)
- Queen's University Belfast (GB)
- Instituto de Salud Carlos III (ES)
- Instituto de Neurociencias (ES)
- Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas (ES)
- Vall d'Hebron Institut de Recerca (ES)
- University of Pennsylvania (US)
Publication Details
- Journal
- Journal of Neuroinflammation
- Published
- 2024-12-23
- DOI
- https://doi.org/10.1186/s12974-024-03323-0
- Citations
- 7
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 1.73
Funders
- Ministerio de Ciencia, Innovación y Universidades
- European Commission
- Generalitat de Catalunya
- Universitat Autònoma de Barcelona
- Agència de Gestió d'Ajuts Universitaris i de Recerca
- European Regional Development Fund
- Agencia Estatal de Investigación