Brief communication: Long-term treatment outcomes of transitioning to dolutegravir-based ART from efavirenz in HIV study participants in Mbeya, Tanzania

Transitioning to dolutegravir maintained high rates of viral suppression comparable to efavirenz, albeit with a slight increase in virologic failure. Dolutegravir was well-tolerated overall despite a high ADR rate. Findings support the ongoing scale-up of dolutegravir in Tanzania and other resource-limited settings while highlighting the need for continued viral load monitoring and pharmacovigilance.

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Publication Details

Journal
AIDS Research and Therapy
Published
2024-12-23
DOI
https://doi.org/10.1186/s12981-024-00662-z
Citations
4
Primary Topic
HIV/AIDS drug development and treatment
Type
article
Field-Weighted Citation Impact
1.56
Controls
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article

Brief communication: Long-term treatment outcomes of transitioning to dolutegravir-based ART from efavirenz in HIV study participants in Mbeya, Tanzania

Clement N. Mweya, Revocatus T. Majula
4 citations
AIDS Research and Therapy
HIV/AIDS drug development and treatment
1.56
article

Brief communication: Long-term treatment outcomes of transitioning to dolutegravir-based ART from efavirenz in HIV study participants in Mbeya, Tanzania

Clement N. Mweya, Revocatus T. Majula
article en
4 citations

Abstract

Transitioning to dolutegravir maintained high rates of viral suppression comparable to efavirenz, albeit with a slight increase in virologic failure. Dolutegravir was well-tolerated overall despite a high ADR rate. Findings support the ongoing scale-up of dolutegravir in Tanzania and other resource-limited settings while highlighting the need for continued viral load monitoring and pharmacovigilance.

AIDS Research and TherapyVol. 21(1)
University of Dar es Salaam (TZ), Mbeya University of Science and Technology (TZ)
Good health and well-being
Openalex Percentile: Top 16%
HIV/AIDS drug development and treatment
1.56
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