Brief communication: Long-term treatment outcomes of transitioning to dolutegravir-based ART from efavirenz in HIV study participants in Mbeya, Tanzania
Transitioning to dolutegravir maintained high rates of viral suppression comparable to efavirenz, albeit with a slight increase in virologic failure. Dolutegravir was well-tolerated overall despite a high ADR rate. Findings support the ongoing scale-up of dolutegravir in Tanzania and other resource-limited settings while highlighting the need for continued viral load monitoring and pharmacovigilance.
Authors
- Clement N. Mweya (ORCID: https://orcid.org/0000-0002-7227-3564)
- Revocatus T. Majula
Institutions
- University of Dar es Salaam (TZ)
- Mbeya University of Science and Technology (TZ)
Publication Details
- Journal
- AIDS Research and Therapy
- Published
- 2024-12-23
- DOI
- https://doi.org/10.1186/s12981-024-00662-z
- Citations
- 4
- Primary Topic
- HIV/AIDS drug development and treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.56