Detection of an internal density change in an anthropomorphic head phantom via tracking of charged nuclear fragments in carbon‐ion radiotherapy
Carbon-ion therapy monitoring with charged nuclear fragments was shown to be capable of detecting clinically relevant density changes in an anthropomorphic head phantom under realistic clinic-like conditions. The complexity of the observed signal requires the development of advanced analysis techniques and underscores the importance of Monte Carlo simulations. The findings have strong implications for the ongoing InViMo clinical trial at HIT, which investigates the feasibility of secondary-ion monitoring for skull-base cancer patients.
Authors
- Semi Harrabi (ORCID: https://orcid.org/0000-0003-1195-7150)
- Laurent Kelleter
- R. Kirchgässner (ORCID: https://orcid.org/0009-0004-1156-6226)
- Oliver Jäkel
- Jürgen Debus (ORCID: https://orcid.org/0000-0002-6411-4811)
- Luisa Schweins
- Pamela Ochoa‐Parra (ORCID: https://orcid.org/0009-0002-7373-7524)
- Andrea Mairani (ORCID: https://orcid.org/0000-0001-6669-7064)
- Marcus Winter
- M. Martišíková
Institutions
- Karlsruhe Institute of Technology (DE)
- German Cancer Research Center (DE)
- Heidelberg University (DE)
- University Hospital Heidelberg (DE)
- Heidelberger Institut für Radioonkologie (DE)
- National Center for Tumor Diseases (DE)
Publication Details
- Journal
- Medical Physics
- Published
- 2024-12-23
- DOI
- https://doi.org/10.1002/mp.17590
- Citations
- 5
- Primary Topic
- Radiation Therapy and Dosimetry
- Type
- article
- Field-Weighted Citation Impact
- 2.09