Long noncoding RNA, PURPL is associated with aneuploidy and its magnitude of expression level is dependent on P53 status
These findings show that PURPL is essential for maintaining chromosomal or genomic stability in mammalian cells. Collectively, the study demonstrated that lncRNA-PURPL significantly contributes to CIN, or aneuploidy.
Authors
- Pushkar Malakar (ORCID: https://orcid.org/0000-0002-2295-4062)
Institutions
- Ramakrishna Mission Vivekananda Educational and Research Institute (IN)
Publication Details
- Journal
- Frontiers in Cell and Developmental Biology
- Published
- 2024-12-23
- DOI
- https://doi.org/10.3389/fcell.2024.1410308
- Citations
- 1
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.29
Funders
- National Institutes of Health
- Science and Engineering Research Board
- National Cancer Institute