The α glycolipid rules the NKT cell TCR
In this issue of JEM, Hosono et al. (https://doi.org/10.1084/jem.20240728) characterize a putative self- glycolipid that engages the iNKT cell TCR when bound to CD1d. The expression and distribution of this compound helps to explain some of the unusual properties of invariant NKT cells.
Authors
- Mitchell Kronenberg (ORCID: https://orcid.org/0000-0001-6318-6445)
- Gabriel Ascui (ORCID: https://orcid.org/0000-0001-6837-3194)
Institutions
- La Jolla Institute for Immunology (US)
- University of California San Diego (US)
Publication Details
- Journal
- The Journal of Experimental Medicine
- Published
- 2024-12-23
- DOI
- https://doi.org/10.1084/jem.20242099
- Citations
- 3
- Primary Topic
- Immune Cell Function and Interaction
- Type
- article
- Field-Weighted Citation Impact
- 0.72
Funders
- National Institutes of Health