Discordance in Claudin 18.2 Expression Between Primary and Metastatic Lesions in Patients With Gastric Cancer
CLDN18.2 expression demonstrates significant heterogeneity between PGC and MGC, with a 20% discordance rate. Comprehensive tissue sampling and reassessment of CLDN18.2 status are crucial, especially before initiating CLDN18.2-targeted therapies.
Authors
- Hyo Yung Yun (ORCID: https://orcid.org/0000-0002-5592-1371)
- Ki Hyeong Lee (ORCID: https://orcid.org/0000-0002-7830-5950)
- Ok-Jun Lee (ORCID: https://orcid.org/0000-0002-5350-8751)
- Jihyun Kwon (ORCID: https://orcid.org/0000-0001-8128-3310)
- Yong‐Pyo Lee (ORCID: https://orcid.org/0000-0002-6153-9742)
- M C Cho
- Hongsik Kim (ORCID: https://orcid.org/0000-0002-9469-6699)
- Hye Sook Han (ORCID: https://orcid.org/0000-0001-6729-8700)
- Yaewon Yang (ORCID: https://orcid.org/0000-0002-1773-134X)
- Seung-Myoung Son (ORCID: https://orcid.org/0000-0002-1646-4649)
- Hee Kyung Kim (ORCID: https://orcid.org/0000-0001-7416-4727)
- Dae Hoon Kim (ORCID: https://orcid.org/0000-0001-9873-4907)
- Chang Gok Woo (ORCID: https://orcid.org/0000-0002-9131-3779)
- Sun Kyung Lee
Institutions
- Chungbuk National University (KR)
- Chungbuk National University Hospital (KR)
Publication Details
- Journal
- Journal of the Korean Gastric Cancer Association
- Published
- 2024-12-24
- DOI
- https://doi.org/10.5230/jgc.2025.25.e2
- Citations
- 9
- Primary Topic
- Gastric Cancer Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 3.77
Funders
- National Research Foundation
- National Research Foundation of Korea