Brain Hypertrophy in Patients With Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis and Its Clinical Correlates
Unilateral mTLE due to hippocampal sclerosis is associated with hypertrophy of the contralateral amygdala. This may represent plasticity to compensate for verbal memory deficits or may be the consequence of seizure spread to the contralateral hemisphere.
Authors
- John S. Duncan (ORCID: https://orcid.org/0000-0002-1373-0681)
- Bo Xiao (ORCID: https://orcid.org/0000-0001-5204-1902)
- Lorenzo Caciagli (ORCID: https://orcid.org/0000-0001-7189-9699)
- Tjardo Postma (ORCID: https://orcid.org/0000-0001-6497-9113)
- Anna Miserocchi
- Jane de Tisi (ORCID: https://orcid.org/0000-0002-7666-2268)
- Meneka K. Sidhu (ORCID: https://orcid.org/0000-0003-3267-9348)
- Gavin P. Winston (ORCID: https://orcid.org/0000-0001-9395-1478)
- Lili Long (ORCID: https://orcid.org/0000-0001-5078-8770)
- Matthias J. Koepp (ORCID: https://orcid.org/0000-0002-4277-8000)
- Daichi Sone (ORCID: https://orcid.org/0000-0001-9617-706X)
- Richard Zubal (ORCID: https://orcid.org/0009-0006-1517-3061)
- Sjoerd B. Vos (ORCID: https://orcid.org/0000-0002-8502-4487)
- Marian Galovic (ORCID: https://orcid.org/0000-0002-2307-071X)
- Christian R. Baumann (ORCID: https://orcid.org/0000-0003-3417-1978)
- Matus Velicky Buecheler (ORCID: https://orcid.org/0009-0003-7711-8250)
- Andrew W. McEvoy (ORCID: https://orcid.org/0000-0002-1078-3761)
Institutions
- Jikei University School of Medicine (JP)
- University of Bern (CH)
- Central South University (CN)
- The University of Western Australia (AU)
- University of Zurich (CH)
- Queen's University (CA)
- University Hospital of Bern (CH)
- University Hospital of Zurich (CH)
- National Hospital for Neurology and Neurosurgery (GB)
- Amsterdam University Medical Centers (NL)
- Xiangya Hospital Central South University (CN)
- University College London (GB)
- Epilepsy Society (GB)
- University of Pennsylvania (US)
- Vrije Universiteit Amsterdam (NL)
Publication Details
- Journal
- Neurology
- Published
- 2024-12-23
- DOI
- https://doi.org/10.1212/wnl.0000000000210182
- Citations
- 12
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 4.63
Funders
- Wellcome Trust
- National Imaging Facility
- National Institute for Health and Care Research
- Eisai
- University College London Hospitals NHS Foundation Trust
- Medical Research Council