Distinguishing Transient From Persistent Brain Structural Changes in Pediatric Patients With Acute Disseminated Encephalomyelitis
We could distinguish between 2 outcomes of VV changes in ADEM: one in which the VV expanded but ultimately returned to normal and one in which the expansions continued after disease onset and treatment but failed to resolve. The latter was associated with reduced brain volume, particularly in deep gray matter structures. This highlights the necessity for patients with ADEM to undergo regular MRI scans to assess whether developing VV expansions indicate a greater risk of permanent brain atrophy.
Authors
- Sonia Waiczies (ORCID: https://orcid.org/0000-0002-9916-9572)
- Matthias Baumann (ORCID: https://orcid.org/0000-0003-4471-8324)
- Frederik Bartels (ORCID: https://orcid.org/0000-0003-3523-4520)
- Jason Michael Millward (ORCID: https://orcid.org/0000-0003-4484-2798)
- Friedemann Paul (ORCID: https://orcid.org/0000-0002-6378-0070)
- Eva‐Maria Wendel (ORCID: https://orcid.org/0000-0002-5242-1830)
- Ines El Naggar (ORCID: https://orcid.org/0000-0003-0685-0914)
- Carsten Finke (ORCID: https://orcid.org/0000-0002-7665-1171)
- Thoralf Niendorf (ORCID: https://orcid.org/0000-0001-7584-6527)
- Elias Pilgrim
- Annikki Bertolini (ORCID: https://orcid.org/0000-0003-4196-022X)
Institutions
- Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- Neurology Neuroimmunology & Neuroinflammation
- Published
- 2024-12-23
- DOI
- https://doi.org/10.1212/nxi.0000000000200337
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00