The relationship between radiographic disc calcification score and FGF4L2 genotype in dachshunds

Most dachshunds with 1 FGF4L2 copy have radiographic disc calcification scores that are associated with substantially lower risk of symptomatic disc disease. Radiographic disc calcification scores are similar in dachshunds with 0 and 1 FGF4L2 copies. Given the high allele frequency of FGF4L2, breeding to produce progeny with 1 FGF4L2 copy is expected to be a more achievable short-term goal for dachshund spinal health breeding programs than breeding for 0 copies. It is recommended that both K-n and FGF4L2 genotype status be considered when choosing dachshund breeding stock.

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Publication Details

Journal
Journal of Veterinary Internal Medicine
Published
2024-12-23
DOI
https://doi.org/10.1111/jvim.17281
Citations
2
Primary Topic
Veterinary Orthopedics and Neurology
Type
article
Field-Weighted Citation Impact
1.28
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article

The relationship between radiographic disc calcification score and FGF4L2 genotype in dachshunds

Michaela L. Sundqvist, Michelle Anne Kutzler, David T. Redden, Stacey Sullivan et al.
2 citations
Journal of Veterinary Internal Medicine
Veterinary Orthopedics and Neurology
1.28
article

The relationship between radiographic disc calcification score and FGF4L2 genotype in dachshunds

Michaela L. Sundqvist, Michelle Anne Kutzler, David T. Redden, Stacey Sullivan, Froydis Hardeng
article en
2 citations

Abstract

Most dachshunds with 1 FGF4L2 copy have radiographic disc calcification scores that are associated with substantially lower risk of symptomatic disc disease. Radiographic disc calcification scores are similar in dachshunds with 0 and 1 FGF4L2 copies. Given the high allele frequency of FGF4L2, breeding to produce progeny with 1 FGF4L2 copy is expected to be a more achievable short-term goal for dachshund spinal health breeding programs than breeding for 0 copies. It is recommended that both K-n and FGF4L2 genotype status be considered when choosing dachshund breeding stock.

Journal of Veterinary Internal MedicineVol. 39(1)
Oregon State University (US), Swedish CLL group (SE), Norwegian Hull Club (Norway) (NO), Auburn University (US)
Openalex Percentile: Top 18%
Veterinary Orthopedics and Neurology
1.28
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The relationship between radiographic disc calcification score and FGF4L2 genotype in dachshunds — Michaela L. Sundqvist, Michelle Anne Kutzler, et al. · Journal of Veterinary Internal Medicine (2024) | TGRS Research Map | TGRS