The relationship between radiographic disc calcification score and FGF4L2 genotype in dachshunds
Most dachshunds with 1 FGF4L2 copy have radiographic disc calcification scores that are associated with substantially lower risk of symptomatic disc disease. Radiographic disc calcification scores are similar in dachshunds with 0 and 1 FGF4L2 copies. Given the high allele frequency of FGF4L2, breeding to produce progeny with 1 FGF4L2 copy is expected to be a more achievable short-term goal for dachshund spinal health breeding programs than breeding for 0 copies. It is recommended that both K-n and FGF4L2 genotype status be considered when choosing dachshund breeding stock.
Authors
- Michaela L. Sundqvist (ORCID: https://orcid.org/0000-0003-2651-6710)
- Michelle Anne Kutzler (ORCID: https://orcid.org/0000-0001-7262-8137)
- David T. Redden (ORCID: https://orcid.org/0000-0002-1016-272X)
- Stacey Sullivan
- Froydis Hardeng
Institutions
- Oregon State University (US)
- Swedish CLL group (SE)
- Norwegian Hull Club (Norway) (NO)
- Auburn University (US)
Publication Details
- Journal
- Journal of Veterinary Internal Medicine
- Published
- 2024-12-23
- DOI
- https://doi.org/10.1111/jvim.17281
- Citations
- 2
- Primary Topic
- Veterinary Orthopedics and Neurology
- Type
- article
- Field-Weighted Citation Impact
- 1.28