Clinical and radiologic distinctions between familial cavernous malformation syndrome and cerebral amyloid angiopathy
Patients with FCCM can be reliably distinguished from CAA by accurately applying the Boston 2.0 criteria, assessing hemorrhagic lesion distribution and types, and assessing for clinical features unique to FCCM. FCCM criteria are proposed. The frequent finding of leukoaraiosis and enlarged perivascular spaces in the centrum semiovale in FCCM patients deserves further investigation.
Authors
- Sherri A. Braksick (ORCID: https://orcid.org/0000-0001-6257-1464)
- James P. Klaas (ORCID: https://orcid.org/0000-0003-1563-528X)
- Petrice Cogswell
- Giuseppe S Lanzino (ORCID: https://orcid.org/0000-0003-1479-465X)
- Kelly D. Flemming (ORCID: https://orcid.org/0000-0001-6021-1190)
- Ross R. Reichard
- Jonathan Graff Radford
Institutions
- Mayo Clinic (US)
- WinnMed (US)
- Mayo Clinic in Arizona (US)
Publication Details
- Journal
- Acta Neurochirurgica
- Published
- 2024-12-23
- DOI
- https://doi.org/10.1007/s00701-024-06400-8
- Primary Topic
- Vascular Malformations Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00