Expression of Concern: Urinary Exosomal microRNA-451-5p Is a Potential Early Biomarker of Diabetic Nephropathy in Rats

After this article [1] was published, concerns were raised that the Fig 4A CTRL week 6 panel and DM week 3 panel appear similar.The corresponding author confirmed that the panels were duplicated inadvertently and supplied the original image data (S1 File), the data underlying the graphs in Fig 4 (S2 File), and a corrected figure.Fig 4. Kidney tissue pathology in rats.Representative (A) PAS and (C) MT stained images of kidney tissue sections from untreated diabetic (DM), non-diabetic control (CTRL) and insulin treated diabetic rats (DM + INS) after 3 rd , 6 th and 9 th weeks of diabetes induction (n = 3/group/time point), Bar graph showing a semi-quantitative analysis for (B) glomerulosclerotic index (GI) and (D) tubulointerstitial fibrosis index (TFI) kidneys tissues from these (n = 3/group/ time point).#p0.05 as compared to 3 rd week within the group by unpaired t-test, (n = 3/time point).*p0.05versus DM+ INS and p0.05 versus CTRL by One-Way ANOVA followed by pair wise multiple comparison (at each time point) testing (n = 3/group).

Publication Details

Journal
PLoS ONE
Published
2024-12-23
DOI
https://doi.org/10.1371/journal.pone.0316405
Citations
1
Primary Topic
Extracellular vesicles in disease
Type
article
Field-Weighted Citation Impact
0.23
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article

Expression of Concern: Urinary Exosomal microRNA-451-5p Is a Potential Early Biomarker of Diabetic Nephropathy in Rats

1 citations
PLoS ONE
Extracellular vesicles in disease
0.23
article

Expression of Concern: Urinary Exosomal microRNA-451-5p Is a Potential Early Biomarker of Diabetic Nephropathy in Rats

article en
1 citations

Abstract

After this article [1] was published, concerns were raised that the Fig 4A CTRL week 6 panel and DM week 3 panel appear similar.The corresponding author confirmed that the panels were duplicated inadvertently and supplied the original image data (S1 File), the data underlying the graphs in Fig 4 (S2 File), and a corrected figure.Fig 4. Kidney tissue pathology in rats.Representative (A) PAS and (C) MT stained images of kidney tissue sections from untreated diabetic (DM), non-diabetic control (CTRL) and insulin treated diabetic rats (DM + INS) after 3 rd , 6 th and 9 th weeks of diabetes induction (n = 3/group/time point), Bar graph showing a semi-quantitative analysis for (B) glomerulosclerotic index (GI) and (D) tubulointerstitial fibrosis index (TFI) kidneys tissues from these (n = 3/group/ time point).#p0.05 as compared to 3 rd week within the group by unpaired t-test, (n = 3/time point).*p0.05versus DM+ INS and p0.05 versus CTRL by One-Way ANOVA followed by pair wise multiple comparison (at each time point) testing (n = 3/group).

PLoS ONEVol. 19(12)
Zero hunger
Openalex Percentile: Top 40%
Extracellular vesicles in disease
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