Delving into female breast cancer: Distinct disease-specific survival outcomes between invasive lobular and ductal carcinomas revealed by propensity score matching
This study provides evidence supporting the existence of significant differences in prognosis between IDC and ILC patients after rigorous matching. The IDC group displayed a significantly better prognosis than the ILC group. Notably, these findings have implications for personalized treatment in clinical practice and contribute to the ongoing academic debate on survival differences between IDC and ILC. However, further research is needed to investigate the biological mechanisms, gene expression, and signaling pathway disparities between IDC and ILC, aiming to provide more targeted guidance for clinical decision-making.
Authors
- Qingxia Li (ORCID: https://orcid.org/0000-0002-1531-2723)
- Lin Kang (ORCID: https://orcid.org/0000-0003-2709-5604)
- Jiaojiao Xue
- Sihan Guo
- Ye Zhou (ORCID: https://orcid.org/0000-0003-1694-2847)
- Yongrui Duan (ORCID: https://orcid.org/0000-0003-4535-8789)
- Yuquan Huang
- Shan Gao (ORCID: https://orcid.org/0000-0003-1066-0531)
- Jian Qing Shi (ORCID: https://orcid.org/0000-0002-2924-1137)
- Tao Zhou
- Wu Zhang
Institutions
- Hebei Medical University (CN)
- North China University of Science and Technology (CN)
- Hebei North University (CN)
- Guilin Medical University (CN)
- Durham University (GB)
- Fourth Hospital of Hebei Medical University (CN)
- Hebei General Hospital (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2024-12-23
- DOI
- https://doi.org/10.1371/journal.pone.0300116
- Primary Topic
- Breast Cancer Treatment Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Hebei Province