Synthesis, Characterization and Antitrypanosomal Activity Of Metal Complexes Of 2-{(E)-[(4-Bromophenyl)imino]methyl}phenol
The current study investigates the Antileishmanial and cytotoxic activity of synthesized Schiff base ligand 2-{(E)-[(4-bromophenyl)imino]methyl}phenol and their Metal complexes prepared by reflux process. Various metal salt is used in complexation like Zn, Cu, Ni, Co and the synthesized compounds is studied structurally with chromatographic technique and checked their solubility in THF, DMSO and CH3COCH3. Such compounds show good Anti-leishmanial activity with no Cytotoxicity which exhibited scarcer negative impacts and could serve as effective substances in Antileishmanial and Cytotoxicity.
Authors
- Zama Jan (ORCID: https://orcid.org/0009-0004-0153-401X)
- Usman Khan (ORCID: https://orcid.org/0000-0003-1899-5563)
- Sara E. Ali (ORCID: https://orcid.org/0000-0003-2671-0521)
- Muhammad Jamshed
Institutions
- Abdul Wali Khan University Mardan (PK)
- Xi'an Jiaotong University (CN)
Publication Details
- Journal
- Journal of Chemistry and Environment
- Published
- 2024-12-15
- DOI
- https://doi.org/10.56946/jce.v3i2.558
- Citations
- 1
- Primary Topic
- Metal complexes synthesis and properties
- Type
- article
- Field-Weighted Citation Impact
- 0.28
Funders
- Abdul Wali Khan University Mardan