Treatment initiation and completion among head and neck squamous cell carcinoma patients in Tanzania

Among the 176 head and neck squamous cell carcinoma (HNSCC) patients, 34% (59) had no treatment documented, 34%(59) had documentation of treatment initiation but not completion, and 33%(58) had documentation of treatment completion based on the modalities started. Univariate logistic regression showed that late-stage disease was associated with increased odds of initiating treatment (OR 8.24, 95% CI 2.05-33.11, p = 0.003) and trends toward completing treatment (OR 7.41, 95% CI 0.90-60.99, p = 0.063). At last visit, 36.9%(65) were alive with a median follow up of 5.6 months (IQR 1.64-12.5 months). A large proportion of HNC patients who presented to MNH and ORCI did not initiate or complete treatment. These metrics are critical to contextualize care outcomes of HNC patients in resource-constrained health systems and develop interventions.

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Publication Details

Journal
BMC Research Notes
Published
2024-12-23
DOI
https://doi.org/10.1186/s13104-024-07045-7
Citations
1
Primary Topic
Head and Neck Cancer Studies
Type
article
Field-Weighted Citation Impact
0.58
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article

Treatment initiation and completion among head and neck squamous cell carcinoma patients in Tanzania

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Treatment initiation and completion among head and neck squamous cell carcinoma patients in Tanzania

Mary Jue Xu, Katherine Van Loon, Aslam Nkya, Beatrice P. Mushi, Atuganile Malango, Sumaiya Haddadi, Elia J. Mmbaga, Dianna Ng, Godfrey Sama, Sikudhani Muya, Patrick K. Ha, Sarah K. Nyagabona, Willybroad Massawe, Sue S. Yom, Li Zhang, Enica Richard
article en
1 citations

Abstract

Among the 176 head and neck squamous cell carcinoma (HNSCC) patients, 34% (59) had no treatment documented, 34%(59) had documentation of treatment initiation but not completion, and 33%(58) had documentation of treatment completion based on the modalities started. Univariate logistic regression showed that late-stage disease was associated with increased odds of initiating treatment (OR 8.24, 95% CI 2.05-33.11, p = 0.003) and trends toward completing treatment (OR 7.41, 95% CI 0.90-60.99, p = 0.063). At last visit, 36.9%(65) were alive with a median follow up of 5.6 months (IQR 1.64-12.5 months). A large proportion of HNC patients who presented to MNH and ORCI did not initiate or complete treatment. These metrics are critical to contextualize care outcomes of HNC patients in resource-constrained health systems and develop interventions.

BMC Research NotesVol. 17(1)
Memorial Sloan Kettering Cancer Center (US), University of British Columbia (CA), Muhimbili University of Health and Allied Sciences (TZ), University of California, San Francisco (US), Muhimbili National Hospital (TZ), East, Central and Southern Africa Health Community (TZ), Ocean Road Cancer Institute (TZ), University of San Francisco (US)
Life below water
Openalex Percentile: Top 27%
Head and Neck Cancer Studies
0.58
DOIOpen Access PDFOpenAlex
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